Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17977215 | 0.90 | ROCK2 (0.47) | ROCK2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25323472 | 0.83 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL3805162 | 0.83 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL29095162 | 0.83 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL4705113 | 0.81 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL1261955 | 0.81 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL31506527 | 0.80 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL31556668 | 0.79 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL5787292 | 0.78 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL26663249 | 0.78 | PDE4B (0.45) | PDE4APDE4BPDE4CPDE4DHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024084390-A1 | COMPOUNDS FOR THE ACTIVATION OF AMPK | PFIZER INC. (US) | 2024-04-25 | — | — | WO | disclosed |