Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15639933 | 0.82 | SCN5A (0.54) | PIK3CAMTORMAP3K14GAASCN5A | |
| SCHEMBL24654977 | 0.80 | CYP1A2 (0.50) | MAP3K14GAASCN5A | |
| SCHEMBL23419244 | 0.80 | SCN5A (0.38) | SCN5ATSHRMAP3K5EIF2AK4 | |
| SCHEMBL21305144 | 0.79 | POLB (0.51) | MAP3K14GAASCN5AFLT3PIK3CD | |
| SCHEMBL12998303 | 0.76 | PIK3CA (0.47) | PIK3CAMTORMAP3K14GAAFLT3 | |
| SCHEMBL3029604 | 0.75 | MAP3K14 (0.49) | PIK3CAMTORMAP3K14GAAFLT3 | |
| SCHEMBL30926487 | 0.75 | SCN5A (0.35) | SCN5A | |
| SCHEMBL16011333 | 0.75 | GAA (0.54) | PIK3CAMTORMAP3K14GAAFLT3 | |
| SCHEMBL21370423 | 0.73 | SCN5A (0.35) | SCN5AEIF2AK4 | |
| SCHEMBL19631457 | 0.73 | CYP1A2 (0.42) | GAASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626423-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024119122-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |