Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.85 |
| ▸ | MEN1 | O00255 | 10/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.85 |
| ▸ | LMNA | P02545 | 4/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.83 |
| ▸ | POLB | P06746 | 2/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | IDH1 | O75874 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27180025 | 1.00 | MAPT (0.85) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL27180922 | 0.92 | MAPT (1.00) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL27180386 | 0.92 | MAPT (0.92) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30926709 | 0.91 | MEN1 (0.87) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL27180448 | 0.91 | ALDH1A1 (1.00) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL27179683 | 0.91 | MEN1 (0.87) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30926946 | 0.90 | MEN1 (0.79) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL27181608 | 0.90 | MEN1 (0.79) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30926692 | 0.90 | MAPT (0.85) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30926792 | 0.90 | MAPT (0.85) | MAPTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | MAPT 4236/4885MEN1 4795/4885KMT2A 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.