Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.63 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27180977 | 1.00 | F10 (0.64) | F10HDAC3HDAC1NCOR2HDAC2 | |
| SCHEMBL8625192 | 0.90 | F10 (0.67) | F10HDAC3HDAC1NCOR2HDAC2 | |
| SCHEMBL8625679 | 0.89 | TUBB4A (0.68) | F10HDAC3HDAC1NCOR2HDAC2 | |
| SCHEMBL8627623 | 0.88 | F10 (0.64) | F10HDAC3HDAC1NCOR2HDAC2 | |
| SCHEMBL27180645 | 0.86 | KMT2A (0.71) | KDRMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL8625175 | 0.86 | FLT1 (0.64) | KDRMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL30926938 | 0.86 | KMT2A (0.71) | KDRMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL8626468 | 0.86 | SMN1; SMN2 (0.69) | F10HDAC3HDAC1NCOR2HDAC2 | |
| SCHEMBL30926935 | 0.84 | KMT2A (0.61) | KDRMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL27180994 | 0.84 | KMT2A (0.61) | KDRMEN1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | F10 4186/4885HDAC3 3268/4885HDAC1 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.