Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.77 |
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | CASP3 | P42574 | 2/20 | 0.72 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.72 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.72 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | DDX3X | O00571 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27181018 | 1.00 | MEN1 (0.77) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL30926657 | 0.87 | CASP3 (0.66) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL27179660 | 0.87 | CASP3 (0.66) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL13532183 | 0.87 | CASP3 (0.85) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL30927031 | 0.87 | CASP3 (0.89) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL27179429 | 0.87 | CASP3 (0.89) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL27179434 | 0.87 | MAPT (1.00) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL14484934 | 0.86 | CASP3 (0.87) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL30926854 | 0.85 | CASP3 (0.76) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL27180605 | 0.85 | CASP3 (0.76) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | MEN1 4795/4885KMT2A 2544/4885MAPT 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.