Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | EGFR | P00533 | 5/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.67 |
| ▸ | KDR | P35968 | 5/20 | 0.67 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179824 | 1.00 | MEN1 (0.71) | MEN1KMT2AEGFRFGFR1KDR | |
| SCHEMBL30927044 | 0.91 | MEN1 (0.76) | MEN1KMT2AEGFRFGFR1KDR | |
| SCHEMBL27179714 | 0.91 | MEN1 (0.76) | MEN1KMT2AEGFRFGFR1KDR | |
| SCHEMBL30926654 | 0.86 | TCF4 (0.69) | MEN1KMT2AEGFRFGFR1KDR | |
| SCHEMBL27180756 | 0.86 | TCF4 (0.69) | MEN1KMT2AEGFRFGFR1KDR | |
| SCHEMBL26463794 | 0.86 | CYP19A1 (0.78) | MEN1KMT2AMAPTHTTCYP19A1 | |
| SCHEMBL30926705 | 0.85 | KMT2A (0.70) | MEN1KMT2AEGFRFGFR1KDR | |
| SCHEMBL27179849 | 0.85 | KMT2A (0.70) | MEN1KMT2AEGFRFGFR1KDR | |
| SCHEMBL21802493 | 0.83 | CYP19A1 (0.69) | MEN1KMT2AEGFRFGFR1KDR | |
| SCHEMBL22863019 | 0.82 | MEN1 (0.73) | MEN1KMT2AKCNK3MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | MEN1 4795/4885KMT2A 2544/4885EGFR 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.