Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27180604 | 1.00 | MEN1 (1.00) | MEN1KMT2ALMNASMN1; SMN2EGFR | |
| SCHEMBL27180159 | 0.86 | MAPT (0.76) | MEN1KMT2ALMNAEGFRFGFR1 | |
| SCHEMBL2825370 | 0.80 | KMT2A (0.79) | MEN1KMT2AEGFRFGFR1KDR | |
| SCHEMBL2941161 | 0.79 | CA12 (0.69) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL27181356 | 0.79 | MEN1 (0.65) | MEN1KMT2ALMNASMN1; SMN2EGFR | |
| SCHEMBL27181139 | 0.79 | KMT2A (0.74) | MEN1KMT2ALMNASMN1; SMN2EGFR | |
| SCHEMBL30926936 | 0.79 | KMT2A (0.74) | MEN1KMT2ALMNASMN1; SMN2EGFR | |
| SCHEMBL27179466 | 0.79 | MEN1 (0.65) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL30926533 | 0.79 | MEN1 (0.65) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL27179484 | 0.79 | ADRB2 (0.67) | MEN1KMT2ALMNAEGFRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | MEN1 4795/4885KMT2A 2544/4885LMNA 4774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.