Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.75 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | SNCA | P37840 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179426 | 1.00 | MEN1 (0.75) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL27179809 | 0.90 | MEN1 (0.70) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL30926740 | 0.90 | MEN1 (0.70) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL27179626 | 0.88 | MAPT (0.63) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL30926454 | 0.88 | MAPT (0.63) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL27181564 | 0.88 | MEN1 (0.65) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL27179818 | 0.87 | MEN1 (0.86) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL30926496 | 0.83 | MAPT (0.63) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL27180859 | 0.83 | MAPT (0.63) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL30926479 | 0.82 | ADORA3 (0.62) | MEN1KMT2ALMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | MEN1 4795/4885KMT2A 2544/4885LMNA 4774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.