Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.78 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.68 |
| ▸ | STAT3 | P40763 | 4/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.68 |
| ▸ | RELA | Q04206 | 3/20 | 0.68 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | PTGES | O14684 | 2/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30928252 | 1.00 | GAA (0.80) | GAAKDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL30966316 | 0.89 | KDM4E (1.00) | GAAKDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL31207225 | 0.89 | KDM4E (1.00) | GAAKDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL29242003 | 0.89 | KDM4E (1.00) | GAAKDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL2743839 | 0.88 | CYP1A2 (1.00) | GAAKDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL2743841 | 0.88 | CYP1A2 (1.00) | GAAKDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL14875151 | 0.88 | KDM4E (0.76) | GAAKDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL14875150 | 0.88 | KDM4E (0.76) | GAAKDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL16454768 | 0.82 | PRMT1 (0.77) | GAAKDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL30179914 | 0.82 | CYP1A2 (0.87) | GAAKDM4ECYP1A2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084645-A | Conjugated ketene skeleton bromophenol compound, preparation method and anti-tumor application | 中国海洋大学 | 2024-05-28 | — | — | CN | claimed |