Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | STAT3 | P40763 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | TFEB | P19484 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31366778 | 0.81 | NFE2L2 (0.54) | NFE2L2CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL30928251 | 0.81 | NFE2L2 (0.54) | NFE2L2CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL1646879 | 0.80 | ERN1 (0.64) | MAPTALDH1A1KDM4ETDP1ERN1 | |
| SCHEMBL16093497 | 0.79 | NFE2L2 (0.62) | NFE2L2CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL16385977 | 0.79 | NFE2L2 (0.62) | NFE2L2CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL1647147 | 0.79 | BACE1 (0.71) | CYP2D6CYP2C9MAPTPTGS2 | |
| SCHEMBL1647144 | 0.79 | BACE1 (0.71) | CYP2D6CYP2C9MAPTPTGS2 | |
| SCHEMBL30928257 | 0.78 | NFE2L2 (0.71) | NFE2L2CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL30928256 | 0.77 | BACE1 (0.64) | NFE2L2CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL2744657 | 0.75 | NFE2L2 (1.00) | NFE2L2CYP1A2CYP2D6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084645-A | Conjugated ketene skeleton bromophenol compound, preparation method and anti-tumor application | 中国海洋大学 | 2024-05-28 | — | — | CN | claimed |
| CN-118084645-A | Conjugated ketene skeleton bromophenol compound, preparation method and anti-tumor application | 中国海洋大学 | 2024-05-28 | — | — | CN | disclosed |