SCHEMBL30928296

SCHEMBL30928296

Cc1cccc(-c2cc(-c3ccccc3)cc(C)n2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.50
NPC1 O15118 5/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 2/20 0.50
KMO O15229 2/20 0.49
XDH P47989 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
ADORA2A P29274 1/20 0.46
ADORA1 P30542 1/20 0.46
ALDH1A1 P00352 1/20 0.45
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ENPP3 O14638 1/20 0.45
IDO1 P14902 1/20 0.45
METAP2 P50579 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4546871 0.91 MEN1 (0.54) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL21031238 0.89 MEN1 (0.49) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL4546976 0.89 MEN1 (0.57) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL16201489 0.89 MEN1 (0.57) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL19986167 0.89 MEN1 (0.49) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL4546950 0.89 MEN1 (0.53) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL4402507 0.89 MEN1 (0.53) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL4546993 0.87 MEN1 (0.51) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL21031239 0.87 MEN1 (0.51) RAB9ANPC1MEN1KMT2AKDM4E
SCHEMBL13203397 0.87 MEN1 (0.51) RAB9ANPC1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164900-A Multifunctional pyridine compound and preparation method and application thereof 昆明理工大学 2024-06-11 CN disclosed