Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | NT5C2 | P49902 | 1/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29259047 | 0.82 | GDA (0.46) | HDAC1HDAC2KDRAURKBENPP1 | |
| SCHEMBL17372610 | 0.80 | NPC1 (0.56) | HDAC1HDAC2NPC1RAB9ABRD4 | |
| SCHEMBL31599206 | 0.80 | HDAC1 (0.40) | HDAC1HDAC2KDRAURKBBRD4 | |
| SCHEMBL29638098 | 0.80 | NPC1 (0.56) | HDAC1HDAC2NPC1RAB9ABRD4 | |
| SCHEMBL545883 | 0.78 | NPC1 (0.38) | HDAC1HDAC2NPC1RAB9AKDR | |
| SCHEMBL17372612 | 0.69 | NPC1 (0.35) | HDAC1HDAC2NPC1RAB9ABRD4 | |
| SCHEMBL38663949 | 0.68 | BRD4 (0.58) | HDAC1HDAC2NPC1RAB9ABRD4 | |
| SCHEMBL28960557 | 0.67 | CYP1A2 (0.51) | HDAC1HDAC2NPC1RAB9AKDR | |
| SCHEMBL3134157 | 0.66 | HDAC1 (0.43) | HDAC1HDAC2NPC1RAB9AGDA | |
| SCHEMBL17165346 | 0.65 | PIK3CA (0.44) | HDAC1HDAC2NPC1RAB9ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119404-A | Immunogenic LNP compositions and methods thereof | 辉瑞公司 | 2024-05-31 | — | — | CN | disclosed |