Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30928300 | 0.80 | HDAC1 (0.38) | HDAC1HDAC2PDPK1JAK2FLT3 | |
| SCHEMBL38663949 | 0.77 | BRD4 (0.58) | HDAC1HDAC2MKNK1BRD4BRAF | |
| SCHEMBL29116496 | 0.77 | GDA (0.37) | HDAC1HDAC2MKNK1XDHGDA | |
| SCHEMBL30454201 | 0.77 | GDA (0.37) | HDAC1HDAC2MKNK1XDHGDA | |
| SCHEMBL27461919 | 0.73 | GDA (0.58) | PDPK1KDRAURKBXDHGDA | |
| SCHEMBL28141587 | 0.73 | DPP4 (0.42) | PDPK1MKNK1GDASRCMGMT | |
| SCHEMBL29259047 | 0.70 | GDA (0.46) | HDAC1HDAC2PDPK1KDRAURKB | |
| SCHEMBL17165346 | 0.69 | PIK3CA (0.44) | HDAC1HDAC2MKNK1XDHGDA | |
| SCHEMBL31258318 | 0.69 | PIK3CA (0.44) | HDAC1HDAC2MKNK1XDHGDA | |
| SCHEMBL17372610 | 0.68 | NPC1 (0.56) | HDAC1HDAC2MKNK1BRD4BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111430-A1 | CHEMICAL MODIFICATIONS IN mRNA POLY(A) TAIL | PRIME MEDICINE, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| WO-2025111452-A2 | CHEMICAL MODIFICATIONS IN PEgRNA and ngRNAs | PRIME MEDICINE, INC. (US) | 2025-05-30 | — | — | WO | disclosed |