Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16684296 | 0.84 | TBXAS1 (0.64) | CYP19A1CYP11B1CYP11B2TBXAS1PDE4A | |
| SCHEMBL30928338 | 0.84 | CYP19A1 (0.56) | CYP19A1CYP11B1CYP11B2TBXAS1PDE4A | |
| SCHEMBL29239321 | 0.79 | TBXAS1 (0.70) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL11475999 | 0.78 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2TBXAS1PDE4A | |
| SCHEMBL11475996 | 0.78 | TBXAS1 (0.72) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL11475995 | 0.78 | TBXAS1 (0.72) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL11474932 | 0.77 | TBXAS1 (0.67) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL12639833 | 0.77 | CYP19A1 (0.68) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL24713772 | 0.77 | CYP11B1 (0.68) | CYP19A1CYP11B1CYP11B2TBXAS1POLB | |
| SCHEMBL29239314 | 0.76 | TBXAS1 (0.57) | CYP19A1CYP11B1CYP11B2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005563-A | N-benzyl imidazole derivative and preparation method and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |