Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 12/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 12/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 12/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.39 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30889633 | 0.81 | PIK3CA (0.44) | CSNK2A2CSNK2BCSNK2A1MAP3K7TAB1 | |
| SCHEMBL27008344 | 0.78 | PIK3CA (0.50) | — | |
| SCHEMBL30433902 | 0.78 | CSNK2A2 (0.47) | CSNK2A2CSNK2BCSNK2A1CYSLTR1CYP1A1 | |
| SCHEMBL27132735 | 0.78 | PIK3CA (0.50) | — | |
| SCHEMBL26662394 | 0.78 | PIK3CA (0.44) | CSNK2A2CSNK2BCSNK2A1MAP3K7TAB1 | |
| SCHEMBL26662391 | 0.78 | PIK3CA (0.44) | CSNK2A2CSNK2BCSNK2A1MAP3K7TAB1 | |
| SCHEMBL30584369 | 0.78 | PIK3CA (0.44) | CSNK2A2CSNK2BCSNK2A1MAP3K7TAB1 | |
| SCHEMBL24913400 | 0.78 | CSNK2A2 (0.55) | CSNK2A2CSNK2BCSNK2A1CYSLTR1CYP1A1 | |
| SCHEMBL31319834 | 0.77 | BRD4 (0.53) | BRD4PIM1PIM2BTK | |
| SCHEMBL910340 | 0.77 | CYP1A1 (0.54) | CSNK2A2CSNK2BCSNK2A1CYSLTR1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182460-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION | 2024-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182460-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PIK3CA, PIK3R4, PIK3R5 | BRD4 3071/4885CSNK2A2 264/4885CSNK2B 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.