Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 5/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30928916 | 0.88 | ALDH1A1 (0.53) | TDP2ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL30928887 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30928912 | 0.86 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30928890 | 0.85 | ALDH1A1 (0.65) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30928915 | 0.85 | CYP1A2 (0.54) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30928924 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30928898 | 0.85 | ALDH1A1 (0.67) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL30928907 | 0.84 | ALDH1A1 (0.49) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL30928899 | 0.84 | ADORA2A (0.55) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30928921 | 0.84 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184594-A | Preparation method of aza-uracil compound, and compound prepared by same and application of aza-uracil compound | 杭州医学院 | 2024-06-14 | — | — | CN | disclosed |