SCHEMBL30929199

SCHEMBL30929199

Cc1cn2cc(Br)nc(C#N)c2n1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 6/20 0.35
KDM5A P29375 1/20 0.33
CDK4 P11802 2/20 0.32
CCND3 P30281 2/20 0.32
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25104604 0.79 GRM5 (0.35) GRM5KDM5ACDK4CCND3
SCHEMBL25105569 0.77 GRM5 (0.33) GRM5KDM5ACDK4CCND3
SCHEMBL5552998 0.76 ADORA1 (0.34) ADORA1
SCHEMBL17375471 0.76 ADORA1 (0.34) ADORA1
SCHEMBL12138525 0.73 ADORA1 (0.33) GRM5ADORA1
SCHEMBL15688674 0.72 L3MBTL1 (0.38) GRM5KDM5ACDK4CCND3
SCHEMBL24164067 0.72 ADORA1 (0.34) ADORA1
SCHEMBL25095872 0.71 RXFP1 (0.39) GRM5KDM5ACDK4CCND3
SCHEMBL17375447 0.70 ADORA1 (0.31) ADORA1
SCHEMBL18263952 0.70 TTK (0.32) ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395892-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING Remix Therapeutics Inc. (US) 2024-07-10 EP disclosed