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Sugi Predict / Compounds / SCHEMBL30929396

SCHEMBL30929396

SCHEMBL30929396

Cc1cc(C)cc(CNc2cnc3n(c2=O)[C@H](C(=O)NCc2ccc(N)nc2C)CC3)c1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 17/20 0.51
▸ F7 P08709 1/20 0.51
▸ F3 P13726 1/20 0.51
▸ PRSS1 P07477 15/20 0.43
▸ PRSS2 P07478 2/20 0.43
▸ PRSS3 P35030 2/20 0.43
▸ KLKB1 P03952 1/20 0.40
▸ F10 P00742 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30929425 0.93 F2 (0.47) F2F7F3PRSS1PRSS2
SCHEMBL30929392 0.93 F2 (0.49) F2F7F3PRSS1PRSS2
SCHEMBL30929397 0.93 F2 (0.47) F2F7F3PRSS1PRSS2
SCHEMBL30929418 0.89 F2 (0.55) F2F7F3PRSS1PRSS2
SCHEMBL30929445 0.89 F2 (0.48) F2F7F3PRSS1PRSS2
SCHEMBL30929454 0.88 F2 (0.48) F2F7F3PRSS1PRSS2
SCHEMBL30929436 0.87 F2 (0.57) F2F7F3PRSS1F10
SCHEMBL30929439 0.87 F2 (0.47) F2F7F3PRSS1PRSS2
SCHEMBL30929433 0.87 F2 (0.49) F2F7F3PRSS1PRSS2
SCHEMBL30929470 0.87 F2 (0.51) F2F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626891-A1 FUSED PYRIMIDINES AS MASP-2 INHIBITORS Omeros Corporation (US) 2025-10-08 — — EP disclosed
WO-2024118840-A1 FUSED PYRIMIDINES AS MASP-2 INHIBITORS OMEROS CORPORATION (US) 2024-06-06 — — WO disclosed