Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | F3 | P13726 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 15/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929396 | 0.87 | F2 (0.51) | F2F7F3 | |
| SCHEMBL30929412 | 0.84 | F2 (0.54) | F2F7F3P2RX7CYP3A4 | |
| SCHEMBL30929436 | 0.82 | F2 (0.57) | F2F7F3P2RX7CYP3A4 | |
| SCHEMBL30929392 | 0.81 | F2 (0.49) | F2F7F3 | |
| SCHEMBL30929426 | 0.81 | F2 (0.52) | F2F7F3P2RX7CYP3A4 | |
| SCHEMBL30929472 | 0.81 | F2 (0.44) | F2F7F3P2RX7CYP3A4 | |
| SCHEMBL30929399 | 0.81 | F2 (0.47) | F2F7F3P2RX7CYP3A4 | |
| SCHEMBL30929425 | 0.81 | F2 (0.47) | F2F7F3 | |
| SCHEMBL30929397 | 0.80 | F2 (0.47) | F2F7F3P2RX7 | |
| SCHEMBL30929415 | 0.77 | F2 (0.44) | F2F7F3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626891-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | Omeros Corporation (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118840-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | OMEROS CORPORATION (US) | 2024-06-06 | — | — | WO | disclosed |