Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929454 | 0.90 | F2 (0.48) | F2F7F3PRSS1PRSS2 | |
| SCHEMBL30929392 | 0.90 | F2 (0.49) | F2F7F3PRSS1F10 | |
| SCHEMBL30929407 | 0.87 | F2 (0.48) | F2F7F3PRSS1F10 | |
| SCHEMBL30929396 | 0.86 | F2 (0.51) | F2F7F3PRSS1F10 | |
| SCHEMBL30929391 | 0.86 | F2 (0.46) | F2F7F3PRSS1F10 | |
| SCHEMBL30929418 | 0.86 | F2 (0.55) | F2F7F3PRSS1F10 | |
| SCHEMBL30929445 | 0.84 | F2 (0.48) | F2F7F3PRSS1PRSS2 | |
| SCHEMBL30929433 | 0.83 | F2 (0.49) | F2F7F3PRSS1F10 | |
| SCHEMBL30929467 | 0.83 | F2 (0.47) | F2F7F3PRSS1PRSS2 | |
| SCHEMBL30929439 | 0.82 | F2 (0.47) | F2F7F3PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626891-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | Omeros Corporation (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118840-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | OMEROS CORPORATION (US) | 2024-06-06 | — | — | WO | disclosed |