Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 6/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929399 | 0.93 | F2 (0.47) | F2F7F3PREPRPS6KB1 | |
| SCHEMBL30929465 | 0.89 | PREP (0.44) | F2F7F3PREPRPS6KB1 | |
| SCHEMBL30929452 | 0.89 | F2 (0.45) | F2F7F3PREPBRD4 | |
| SCHEMBL30929417 | 0.88 | F2 (0.41) | F2F7F3PREPRPS6KB1 | |
| SCHEMBL30929448 | 0.88 | F2 (0.42) | F2F7F3PREPBRD4 | |
| SCHEMBL30929457 | 0.85 | BRD4 (0.50) | F2F7F3PREPRPS6KB1 | |
| Ammonia Solution, Strong SCHEMBL30929419 | 0.84 | BRD4 (0.49) | F2F7F3PREPRPS6KB1 | |
| SCHEMBL30929440 | 0.82 | F2 (0.43) | F2F7F3PREP | |
| SCHEMBL31486546 | 0.80 | RPS6KB1 (0.39) | PREPRPS6KB1RIPK1TLR2 | |
| SCHEMBL30929415 | 0.80 | F2 (0.44) | F2F7F3PREPRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626891-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | Omeros Corporation (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118840-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | OMEROS CORPORATION (US) | 2024-06-06 | — | — | WO | disclosed |