Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 13/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ARNT | P27540 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929451 | 0.89 | F2 (0.44) | PREPF2F7F3RPS6KB1 | |
| SCHEMBL30929452 | 0.88 | F2 (0.45) | PREPF2F7F3P2RX7 | |
| SCHEMBL30929478 | 0.87 | F2 (0.41) | PREPF2F7F3AURKA | |
| SCHEMBL30929399 | 0.83 | F2 (0.47) | PREPF2F7F3RPS6KB1 | |
| SCHEMBL30929448 | 0.79 | F2 (0.42) | PREPF2F7F3P2RX7 | |
| SCHEMBL30929440 | 0.78 | F2 (0.43) | PREPF2F7F3P2RX7 | |
| SCHEMBL30929457 | 0.78 | BRD4 (0.50) | PREPF2F7F3AURKA | |
| SCHEMBL30929474 | 0.78 | PREP (0.43) | PREPF2F7F3P2RX7 | |
| SCHEMBL30929417 | 0.78 | F2 (0.41) | PREPF2F7F3RPS6KB1 | |
| Ammonia Solution, Strong SCHEMBL30929419 | 0.77 | BRD4 (0.49) | PREPF2F7F3AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626891-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | Omeros Corporation (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118840-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | OMEROS CORPORATION (US) | 2024-06-06 | — | — | WO | disclosed |