Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354613 | 0.83 | POLB (0.49) | TTRAPPPTPN1MAPTMEN1 | |
| SCHEMBL3354607 | 0.83 | POLB (0.49) | TTRAPPPTPN1MAPTMEN1 | |
| SCHEMBL27736560 | 0.73 | ALDH1A1 (0.73) | TTRAPPPTPN1MAPTMEN1 | |
| SCHEMBL953856 | 0.69 | ALDH1A1 (0.44) | TTRAPPPTPN1MAPTMEN1 | |
| SCHEMBL953855 | 0.69 | ALDH1A1 (0.44) | TTRAPPPTPN1MAPTMEN1 | |
| SCHEMBL958846 | 0.69 | ALDH1A1 (0.58) | TTRAPPPTPN1MAPTMEN1 | |
| SCHEMBL958847 | 0.69 | ALDH1A1 (0.58) | TTRAPPPTPN1MAPTMEN1 | |
| SCHEMBL22877141 | 0.69 | MAPT (0.48) | MAPTMEN1KMT2ALMNARAB9A | |
| SCHEMBL8856037 | 0.68 | SMN1; SMN2 (0.43) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL956043 | 0.68 | ALDH1A1 (0.43) | TTRAPPPTPN1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626865-A1 | CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS | Protego Biopharma, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024118810-A1 | CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS | PROTEGO BIOPHARMA, INC. (US) | 2024-06-06 | — | — | WO | disclosed |