Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81701 | 0.89 | NAMPT (0.55) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL82395 | 0.86 | NAMPT (0.41) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL82755 | 0.85 | NAMPT (0.40) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL83213 | 0.85 | NAMPT (0.40) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL83517 | 0.80 | MEN1 (0.42) | — | |
| SCHEMBL3080177 | 0.80 | HDAC3 (0.47) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL3068565 | 0.79 | NAMPT (0.49) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL3073909 | 0.73 | NAMPT (0.76) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL3073910 | 0.73 | NAMPT (0.76) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL82028 | 0.73 | HTR1A (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100227896-A1 | USE OF VITAMIN PP COMPOUNDS | ASTELLAS DEUTSCHLAND GMBH (DE) | 2010-09-09 | — | — | US | claimed |
| EP-1079832-B1 | USE OF VITAMIN PP COMPOUNDS | KLINGE CO CHEM PHARM FAB (DE) | 2005-11-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227896-A1 | USE OF VITAMIN PP COMPOUNDS | PNPO, NAMPT, NAPRT | NAMPT 2/4885CYP3A4 905/4885CYP2C9 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.