SCHEMBL30930374

SCHEMBL30930374

COC(=O)C1CCc2[nH]nc(CN(C(=O)Nc3ccc(F)c(Cl)c3)c3ccc(OC)nc3)c2C1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MCHR1 Q99705 10/20 0.36
▸ OXTR P30559 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ PABPC1 P11940 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ MKNK1 Q9BUB5 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CSF1R P07333 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30930323 0.94 MCHR1 (0.36) MCHR1OXTRMEN1PABPC1KMT2A
SCHEMBL30930328 0.91 MCHR1 (0.38) MCHR1OXTRMEN1PABPC1KMT2A
SCHEMBL30930351 0.90 MCHR1 (0.36) MCHR1OXTRMEN1PABPC1KMT2A
SCHEMBL30930466 0.90 MCHR1 (0.36) MCHR1OXTRMEN1PABPC1KMT2A
SCHEMBL30930463 0.88 MEN1 (0.38) MCHR1OXTRMEN1PABPC1KMT2A
SCHEMBL30930428 0.88 MEN1 (0.38) MCHR1OXTRMEN1PABPC1KMT2A
SCHEMBL30930420 0.86 SMN1; SMN2 (0.36) MCHR1OXTRMEN1PABPC1KMT2A
SCHEMBL30930454 0.85 MEN1 (0.38) MCHR1OXTRMEN1PABPC1KMT2A
SCHEMBL30930461 0.85 MEN1 (0.36) MCHR1OXTRMEN1PABPC1KMT2A
SCHEMBL30930311 0.84 MCHR1 (0.38) MCHR1OXTRMEN1PABPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103363-A Novel capsid assembly inhibitor 南韩商AM科学股份有限公司 2024-05-28 — — CN claimed
US-20250009742-A1 NOVEL CAPSID ASSEMBLY INHIBITORS META-IMMUNE, INC. (KR) 2025-01-09 — — US disclosed
CN-118103363-A Novel capsid assembly inhibitor 南韩商AM科学股份有限公司 2024-05-28 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250009742-A1 NOVEL CAPSID ASSEMBLY INHIBITORS ZC3HAV1, ZC3HAV1L, MAVS MCHR1 3260/4885OXTR 4861/4885MEN1 4401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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