SCHEMBL30930600

SCHEMBL30930600

O=C1CCC(N2Cc3cc(-c4cccc(C(F)(F)F)n4)ccc3C2=O)C(=O)N1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 12/20 0.59
IKZF2 Q9UKS7 7/20 0.52
IKZF1 Q13422 1/20 0.51
CSNK1A1 P48729 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23860893 0.85 CRBN (0.65) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL30168942 0.85 CRBN (0.65) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27389462 0.85 CRBN (0.65) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL30930655 0.85 CRBN (0.65) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL30133310 0.85 CRBN (0.65) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL23860963 0.83 CRBN (0.56) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL23861021 0.83 CRBN (0.56) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL30133311 0.83 CRBN (0.56) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL30168930 0.83 CRBN (0.56) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL25242812 0.82 CRBN (0.57) CRBNIKZF2IKZF1CSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4612140-A1 NEK7 DEGRADERS AND METHODS OF USE THEREOF Captor Therapeutics S.A. (PL) 2025-09-10 EP disclosed
WO-2024094819-A1 NEK7 DEGRADERS AND METHODS OF USE THEREOF CAPTOR THERAPEUTICS S.A. (PL) 2024-05-10 WO disclosed