SCHEMBL30930608

SCHEMBL30930608

CC(C)(C)OC(=O)N1CCCCN1c1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 9/20 0.54
▸ IKZF2 Q9UKS7 8/20 0.49
▸ CSNK1A1 P48729 2/20 0.48
▸ WIZ O95785 2/20 0.48
▸ GSPT1 P15170 1/20 0.45
▸ DDB1 Q16531 1/20 0.45
▸ IKZF3 Q9UKT9 1/20 0.45
▸ IKZF1 Q13422 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27301548 0.84 CRBN (0.56) CRBNIKZF2CSNK1A1WIZDDB1
SCHEMBL20046704 0.84 CRBN (0.56) CRBNIKZF2CSNK1A1WIZDDB1
SCHEMBL31611548 0.84 CRBN (0.56) CRBNIKZF2CSNK1A1WIZDDB1
SCHEMBL30720192 0.84 CRBN (0.56) CRBNIKZF2CSNK1A1WIZDDB1
SCHEMBL30720169 0.84 CRBN (0.56) CRBNIKZF2CSNK1A1WIZDDB1
SCHEMBL29547522 0.84 CRBN (0.56) CRBNIKZF2CSNK1A1WIZDDB1
SCHEMBL20231651 0.84 CRBN (0.53) CRBNIKZF2CSNK1A1WIZDDB1
SCHEMBL25929611 0.82 CRBN (0.49) CRBNIKZF2CSNK1A1WIZDDB1
SCHEMBL30930637 0.82 CRBN (0.55) CRBNIKZF2WIZDDB1IKZF1
SCHEMBL29767388 0.82 CRBN (0.55) CRBNIKZF2WIZDDB1IKZF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4612140-A1 NEK7 DEGRADERS AND METHODS OF USE THEREOF Captor Therapeutics S.A. (PL) 2025-09-10 — — EP disclosed
WO-2024094819-A1 NEK7 DEGRADERS AND METHODS OF USE THEREOF CAPTOR THERAPEUTICS S.A. (PL) 2024-05-10 — — WO disclosed
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