Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.55 |
| ▸ | IKZF2 | Q9UKS7 | 15/20 | 0.53 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.51 |
| ▸ | WIZ | O95785 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27284747 | 1.00 | CRBN (0.55) | CRBNIKZF2IKZF1WIZDDB1 | |
| SCHEMBL27284718 | 1.00 | CRBN (0.55) | CRBNIKZF2IKZF1WIZDDB1 | |
| SCHEMBL29767388 | 1.00 | CRBN (0.55) | CRBNIKZF2IKZF1WIZDDB1 | |
| SCHEMBL27284779 | 0.97 | CRBN (0.56) | CRBNIKZF2IKZF1DDB1 | |
| SCHEMBL30930634 | 0.88 | IKZF2 (0.39) | CRBNIKZF2IKZF1WIZDDB1 | |
| SCHEMBL30797121 | 0.87 | CRBN (0.49) | CRBNIKZF2IKZF1WIZ | |
| SCHEMBL28575771 | 0.86 | IKZF2 (0.61) | CRBNIKZF2WIZDDB1 | |
| SCHEMBL29767379 | 0.86 | CRBN (0.53) | CRBNIKZF2IKZF1DDB1 | |
| SCHEMBL24572309 | 0.86 | IKZF2 (0.57) | CRBNIKZF2IKZF1DDB1 | |
| SCHEMBL31442921 | 0.86 | CRBN (0.48) | CRBNIKZF2IKZF1WIZDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612140-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | Captor Therapeutics S.A. (PL) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024096753-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024094819-A1 | NEK7 DEGRADERS AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2024-05-10 | — | — | WO | disclosed |