Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.44 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.42 |
| ▸ | WIZ | O95785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27284779 | 0.90 | CRBN (0.56) | CRBNIKZF2IKZF1CSNK1A1SALL4 | |
| SCHEMBL30797272 | 0.89 | CRBN (0.49) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL29767388 | 0.87 | CRBN (0.55) | CRBNIKZF2IKZF1WIZ | |
| SCHEMBL27284718 | 0.87 | CRBN (0.55) | CRBNIKZF2IKZF1WIZ | |
| SCHEMBL30930637 | 0.87 | CRBN (0.55) | CRBNIKZF2IKZF1WIZ | |
| SCHEMBL27284747 | 0.87 | CRBN (0.55) | CRBNIKZF2IKZF1WIZ | |
| SCHEMBL30797388 | 0.84 | CRBN (0.56) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30797138 | 0.81 | CRBN (0.60) | CRBNIKZF2IKZF1 | |
| SCHEMBL30797297 | 0.81 | CRBN (0.62) | CRBNIKZF2IKZF1 | |
| SCHEMBL30930608 | 0.80 | CRBN (0.54) | CRBNIKZF2IKZF1CSNK1A1WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |