SCHEMBL30930699

SCHEMBL30930699

CCOC(=O)/C=C(/COCc1ccccc1)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
CSNK1D P48730 1/20 0.41
ALDH1A1 P00352 1/20 0.40
CES1 P23141 1/20 0.40
HCAR2 Q8TDS4 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
LMNA P02545 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PPID Q08752 1/20 0.37
MDM4 O15151 1/20 0.37
MDM2 Q00987 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275025 0.83 CES1 (0.47) MAPTALDH1A1CES1LMNAL3MBTL1
SCHEMBL1275027 0.83 CES1 (0.47) MAPTALDH1A1CES1LMNAL3MBTL1
SCHEMBL1144398 0.80 MAPT (0.46) MAPTCSNK1DALDH1A1HCAR2NR1H4
SCHEMBL1144400 0.80 MAPT (0.46) MAPTCSNK1DALDH1A1HCAR2NR1H4
SCHEMBL1874593 0.75 TACR1 (0.48)
SCHEMBL1874592 0.75 TACR1 (0.48)
SCHEMBL52219 0.74 ALDH1A1 (0.52) MAPTCSNK1DALDH1A1NR1H4LMNA
SCHEMBL13924823 0.73 NR1H4 (0.49) MAPTALDH1A1HCAR2NR1H4LMNA
SCHEMBL31723025 0.73 CES1 (0.60) ALDH1A1CES1
SCHEMBL31723315 0.73 TSHR (0.44) MAPTCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4647434-A1 MODULATOR FOR PROMOTING BINDING OF BUTYROPHILIN 3A1/2A1 Unicet Biotech Co., LLC (CN) 2025-11-12 EP disclosed
EP-4647435-A1 MODULATOR FOR PROMOTING BINDING OF BUTYROPHILIN 3A1/2A1 Unicet Biotech. LLC (CN) 2025-11-12 EP disclosed
WO-2024146629-A1 MODULATOR FOR PROMOTING BINDING OF BUTYROPHILIN 3A1/2A1 北京清辉联诺生物科技有限责任公司 2024-07-11 WO disclosed