SCHEMBL30930722

SCHEMBL30930722

C[C@@H](OC(C)(C)C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 2/20 0.49
TP53 P04637 2/20 0.49
MDM2 Q00987 1/20 0.48
IDO1 P14902 1/20 0.47
CASP3 P42574 3/20 0.45
TNF P01375 2/20 0.45
PPARA Q07869 1/20 0.43
SLC17A5 Q9NRA2 1/20 0.43
TLR2 O60603 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30646401 1.00 MDM4 (0.49) MDM4TP53MDM2IDO1CASP3
SCHEMBL30930723 1.00 MDM4 (0.49) MDM4TP53MDM2IDO1CASP3
SCHEMBL31554857 0.92 MDM4 (0.51) MDM4TP53MDM2IDO1CASP3
SCHEMBL30291750 0.89 MDM4 (0.49) MDM4TP53MDM2IDO1CASP3
SCHEMBL9183629 0.87 MDM4 (0.49) MDM4TP53MDM2CASP3TNF
SCHEMBL31512913 0.86 CASP3 (0.47) MDM4TP53CASP3
SCHEMBL29402289 0.86 MDM4 (0.51) MDM4TP53MDM2IDO1CASP3
SCHEMBL119402 0.85 CASP3 (0.50) MDM4TP53CASP3
SCHEMBL2367241 0.85 CASP3 (0.50) MDM4TP53CASP3
SCHEMBL2366563 0.85 CASP3 (0.50) MDM4TP53CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120137003-A Method for chemically synthesizing glycosylated insulin 中国医学科学院药物研究所 2025-06-13 CN claimed
EP-4611793-A1 INSULIN DERIVATIVES Ustav organicke chemie a biochemie Akademie ved CR, v.v.i. (CZ) 2025-09-10 EP disclosed
CN-120137003-A Method for chemically synthesizing glycosylated insulin 中国医学科学院药物研究所 2025-06-13 CN disclosed
CN-119219745-A Preparation of tel method of poisein 深圳翰宇药业股份有限公司 2024-12-31 CN disclosed
CN-118047852-A Method for preparing telmisappride 深圳翰宇药业股份有限公司 2024-05-17 CN disclosed
WO-2024094237-A1 INSULIN DERIVATIVES USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CR, V. V. I. (CZ) 2024-05-10 WO disclosed