SCHEMBL30930805

SCHEMBL30930805

Nc1ncnc2c1ncn2[C@@H]1O[C@H](C[S+](CF)CC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 5/20 0.78
AMD1 P17707 2/20 0.78
NNMT P40261 4/20 0.70
DOT1L Q8TEK3 5/20 0.69
EHMT2 Q96KQ7 4/20 0.69
PCMT1 P22061 3/20 0.69
NSD2 O96028 3/20 0.69
SETD7 Q8WTS6 3/20 0.69
PRMT5 O14744 3/20 0.69
PRMT1 Q99873 3/20 0.69
NSD3 Q9BZ95 2/20 0.69
TRDMT1 O14717 2/20 0.69
INMT O95050 2/20 0.69
METTL3 Q86U44 2/20 0.69
EHMT1 Q9H9B1 2/20 0.69
METTL14 Q9HCE5 2/20 0.69
RNMT O43148 1/20 0.69
TPMT P51580 1/20 0.69
NSD1 Q96L73 1/20 0.69
SETD2 Q9BYW2 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2287080 0.91 CARM1 (0.81) CARM1AMD1NNMTDOT1LEHMT2
SCHEMBL2287096 0.91 CARM1 (0.81) CARM1AMD1NNMTDOT1LEHMT2
SCHEMBL2287090 0.91 CARM1 (0.81) CARM1AMD1NNMTDOT1LEHMT2
SCHEMBL30965845 0.91 CARM1 (0.78) CARM1AMD1NNMTDOT1LEHMT2
SCHEMBL2284758 0.90 CARM1 (0.79) CARM1AMD1NNMTDOT1LEHMT2
SCHEMBL2284776 0.90 CARM1 (0.79) CARM1AMD1NNMTDOT1LEHMT2
SCHEMBL2284764 0.90 CARM1 (0.79) CARM1AMD1NNMTDOT1LEHMT2
SCHEMBL31425173 0.89 CARM1 (0.72) CARM1AMD1NNMTDOT1LEHMT2
SCHEMBL2293226 0.89 CARM1 (0.74) CARM1AMD1NNMTDOT1LEHMT2
SCHEMBL2288248 0.89 CARM1 (0.74) CARM1AMD1NNMTDOT1LEHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119876074-A SAM analogues and uses thereof 天津大学 2025-04-25 CN disclosed
CN-118048338-B SAM analogue, SAM dependent methyltransferase mutant and application thereof 天津大学 2025-04-15 CN disclosed
CN-118048338-A SAM analogue, SAM dependent methyltransferase mutant and application thereof 天津大学 2024-05-17 CN disclosed