Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 6/20 | 0.79 |
| ▸ | AMD1 | P17707 | 2/20 | 0.79 |
| ▸ | PRMT1 | Q99873 | 4/20 | 0.69 |
| ▸ | PCMT1 | P22061 | 3/20 | 0.69 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.69 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.69 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.69 |
| ▸ | PNMT | P11086 | 2/20 | 0.69 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.69 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.69 |
| ▸ | PRMT7 | Q9NVM4 | 2/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.69 |
| ▸ | KDR | P35968 | 1/20 | 0.69 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.69 |
| ▸ | NNMT | P40261 | 3/20 | 0.69 |
| ▸ | SETD2 | Q9BYW2 | 3/20 | 0.68 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.68 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.68 |
| ▸ | NSD2 | O96028 | 4/20 | 0.68 |
| ▸ | SETD7 | Q8WTS6 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2284764 | 1.00 | CARM1 (0.79) | CARM1AMD1PRMT1PCMT1PRMT5 | |
| SCHEMBL2284776 | 1.00 | CARM1 (0.79) | CARM1AMD1PRMT1PCMT1PRMT5 | |
| SCHEMBL2287080 | 0.94 | CARM1 (0.81) | CARM1AMD1PRMT1PCMT1PRMT5 | |
| SCHEMBL2287096 | 0.94 | CARM1 (0.81) | CARM1AMD1PRMT1PCMT1PRMT5 | |
| SCHEMBL2287090 | 0.94 | CARM1 (0.81) | CARM1AMD1PRMT1PCMT1PRMT5 | |
| SCHEMBL30930805 | 0.90 | CARM1 (0.78) | CARM1AMD1PRMT1PCMT1PRMT5 | |
| SCHEMBL30965845 | 0.90 | CARM1 (0.78) | CARM1AMD1PRMT1PCMT1PRMT5 | |
| SCHEMBL2284468 | 0.89 | CARM1 (0.73) | CARM1AMD1PRMT1PCMT1PRMT5 | |
| SCHEMBL2284459 | 0.89 | CARM1 (0.73) | CARM1AMD1PRMT1PCMT1PRMT5 | |
| SCHEMBL2284452 | 0.89 | CARM1 (0.73) | CARM1AMD1PRMT1PCMT1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008007-B2 | S-adenosyl-L-methionine analogs with extended activated groups for transfer by methyltransferases | RWTH AACHEN (DE) | 2011-08-30 | — | — | US | disclosed |
| EP-1874790-B1 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2010-08-18 | — | — | EP | disclosed |
| US-20090018101-A1 | S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2009-01-15 | — | — | US | disclosed |
| EP-1874790-A2 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH Aachen (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108678-A2 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2006-10-19 | — | — | WO | disclosed |
| EP-1712557-A1 | New s-adenosyl-L-methionine analogues with extended activated groups for transfer by methyltransferases | RWTH Aachen (DE) | 2006-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018101-A1 | S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | BHMT2, MSRB3, PRMT3 | CARM1 35/4885AMD1 20/4885PRMT1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.