Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 9/20 | 0.54 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551783 | 1.00 | FURIN (0.54) | FURINCACNA1IKCNH2ACHEFAAH | |
| SCHEMBL31540760 | 0.87 | CACNA1I (0.58) | FURINCACNA1IKCNH2ACHECCR3 | |
| SCHEMBL30931839 | 0.83 | CACNA1I (0.54) | FURINCACNA1IKCNH2ACHECCR3 | |
| SCHEMBL21550897 | 0.83 | CACNA1I (0.54) | FURINCACNA1IKCNH2ACHECCR3 | |
| SCHEMBL21550726 | 0.82 | FURIN (0.53) | FURINCACNA1IKCNH2ACHEFAAH | |
| SCHEMBL21551498 | 0.82 | FURIN (0.57) | FURINCACNA1IKCNH2 | |
| SCHEMBL30931751 | 0.82 | FURIN (0.57) | FURINCACNA1IKCNH2 | |
| SCHEMBL21551532 | 0.82 | FURIN (0.53) | FURINCACNA1IKCNH2ACHEFAAH | |
| SCHEMBL31540798 | 0.82 | CACNA1I (0.53) | FURINCACNA1IKCNH2ACHECCR3 | |
| SCHEMBL31540755 | 0.82 | CACNA1I (0.53) | FURINCACNA1IKCNH2ACHECCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |