Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1I | Q9P0X4 | 8/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.53 |
| ▸ | FURIN | P09958 | 7/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31540760 | 0.94 | CACNA1I (0.58) | CACNA1IKCNH2FURINCCR3ACHE | |
| SCHEMBL31540755 | 0.91 | CACNA1I (0.53) | CACNA1IKCNH2FURINCCR3ACHE | |
| SCHEMBL21550897 | 0.88 | CACNA1I (0.54) | CACNA1IKCNH2FURINCCR3ACHE | |
| SCHEMBL30931839 | 0.88 | CACNA1I (0.54) | CACNA1IKCNH2FURINCCR3ACHE | |
| SCHEMBL31540785 | 0.87 | CACNA1I (0.48) | CACNA1IKCNH2FURINCCR3TP53 | |
| Hydrochloric Acid SCHEMBL29891250 | 0.87 | CACNA1I (0.53) | CACNA1IKCNH2FURINCCR3ACHE | |
| SCHEMBL31540775 | 0.85 | CACNA1I (0.50) | CACNA1IKCNH2FURINCCR3TP53 | |
| SCHEMBL31540756 | 0.85 | CACNA1I (0.57) | CACNA1IKCNH2FURINCCR3TP53 | |
| SCHEMBL31540781 | 0.85 | CXCR4 (0.50) | CACNA1IKCNH2FURINCCR3MAPT | |
| SCHEMBL31540765 | 0.85 | CACNA1I (0.52) | CACNA1IKCNH2FURINACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068371-A1 | INHIBITORS OF THE PROPROTEIN CONVERTASE FURIN, METHODS OF PRODUCTION THEREOF AND USE | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2025-04-03 | — | — | WO | disclosed |