Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3093196 | 0.94 | MAPT (0.49) | CYP1A2CYP2D6CYP2C19MAPTCA1 | |
| SCHEMBL2064890 | 0.92 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C19MAPTLMNA | |
| SCHEMBL20210670 | 0.92 | CYP2D6 (0.54) | CYP1A2CYP2D6CYP2C19LMNAALDH1A1 | |
| SCHEMBL3096149 | 0.87 | CYP1A2 (0.42) | CYP1A2CYP2D6CYP2C19CYP4F2CYP4A11 | |
| SCHEMBL3096170 | 0.82 | CYP1A2 (0.42) | CYP1A2CYP2D6CYP2C19MAPTCA12 | |
| SCHEMBL3098898 | 0.81 | CYP1A2 (0.37) | CYP1A2CYP2D6CYP2C19MAPTCA12 | |
| SCHEMBL6563889 | 0.77 | ALDH1A1 (0.53) | MAPTCYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL3098917 | 0.77 | MAPT (0.42) | CYP1A2CYP2D6CYP2C19MAPTALDH1A1 | |
| SCHEMBL2788007 | 0.75 | CYP1A2 (0.45) | CYP1A2CYP2D6CYP2C19MAPTCA12 | |
| SCHEMBL1648605 | 0.72 | TSHR (0.43) | CYP1A2CYP2D6CYP2C19MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799892-B2 | Method of making polybutylene terephthalate and compositions and articles comprising the same | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-09-21 | — | — | US | claimed |
| US-20090275698-A1 | Method of Making Polybutylene Terephthalate and Compositions and Articles Comprising the Same | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2009-11-05 | — | — | US | claimed |
| US-7799892-B2 | Method of making polybutylene terephthalate and compositions and articles comprising the same | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-09-21 | — | — | US | disclosed |
| US-20090275698-A1 | Method of Making Polybutylene Terephthalate and Compositions and Articles Comprising the Same | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2009-11-05 | — | — | US | disclosed |