Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 9/20 | 0.40 |
| ▸ | TYK2 | P29597 | 8/20 | 0.40 |
| ▸ | JAK1 | P23458 | 8/20 | 0.39 |
| ▸ | JAK3 | P52333 | 6/20 | 0.39 |
| ▸ | STAT3 | P40763 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31580378 | 0.93 | CREBBP (0.40) | CREBBPKDM5AJAK2TYK2JAK1 | |
| SCHEMBL31589834 | 0.87 | CREBBP (0.41) | CREBBPUSP30KITRET | |
| SCHEMBL31590468 | 0.87 | KIT (0.48) | CREBBPJAK2TYK2JAK1JAK3 | |
| SCHEMBL31589890 | 0.87 | CREBBP (0.44) | CREBBPUSP30RET | |
| SCHEMBL30932003 | 0.85 | KIT (0.41) | CREBBPJAK2TYK2JAK1JAK3 | |
| SCHEMBL30931984 | 0.84 | CREBBP (0.43) | CREBBPKDM5AABL1USP30RET | |
| SCHEMBL31590410 | 0.84 | CREBBP (0.40) | CREBBPUSP30RET | |
| SCHEMBL30932039 | 0.84 | RET (0.44) | CREBBPKDM5AABL1USP30RET | |
| SCHEMBL31589666 | 0.83 | JAK2 (0.41) | CREBBPJAK2TYK2JAK1JAK3 | |
| SCHEMBL30932021 | 0.81 | RET (0.41) | CREBBPRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120051471-A | Novel heterocyclic compound | 首药控股(北京)股份有限公司 | 2025-05-27 | — | — | CN | disclosed |
| WO-2025102600-A1 | NOVEL HETEROCYCLIC COMPOUND | 首药控股(北京)股份有限公司 | 2025-05-22 | — | — | WO | disclosed |
| WO-2024083111-A1 | NOVEL HETEROCYCLIC COMPOUNDS | 首药控股(北京)股份有限公司 | 2024-04-25 | — | — | WO | disclosed |