Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 12/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590468 | 0.93 | KIT (0.48) | KITCREBBPJAK2JAK1TYK2 | |
| SCHEMBL31580378 | 0.88 | CREBBP (0.40) | KITCREBBPJAK2JAK1TYK2 | |
| SCHEMBL30931972 | 0.85 | CREBBP (0.41) | KITCREBBPJAK2JAK1TYK2 | |
| SCHEMBL31589834 | 0.85 | CREBBP (0.41) | KITCREBBPRETUSP30 | |
| SCHEMBL31589890 | 0.85 | CREBBP (0.44) | CREBBPRETUSP30PIK3CA | |
| SCHEMBL30932027 | 0.85 | RET (0.46) | CREBBPJAK2RETUSP30 | |
| SCHEMBL31590410 | 0.85 | CREBBP (0.40) | CREBBPRETUSP30 | |
| SCHEMBL30931984 | 0.82 | CREBBP (0.43) | CREBBPRETUSP30PIK3CA | |
| SCHEMBL30932039 | 0.82 | RET (0.44) | CREBBPRETUSP30 | |
| SCHEMBL31589666 | 0.81 | JAK2 (0.41) | CREBBPJAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120051471-A | Novel heterocyclic compound | 首药控股(北京)股份有限公司 | 2025-05-27 | — | — | CN | disclosed |
| WO-2024083111-A1 | NOVEL HETEROCYCLIC COMPOUNDS | 首药控股(北京)股份有限公司 | 2024-04-25 | — | — | WO | disclosed |