SCHEMBL30932075

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](N)CCCCN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)O)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC

nearest known ligand 0.72

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	5/20	0.72

▸	HCRTR1	O43613	1/20	0.64

▸	HCRTR2	O43614	1/20	0.64

▸	RAMP1	O60894	1/20	0.64

▸	RAMP2	O60895	1/20	0.64

▸	RAMP3	O60896	1/20	0.64

▸	CALCRL	Q16602	1/20	0.64

▸	F2	P00734	4/20	0.64

▸	NPY2R	P49146	6/20	0.61

▸	NPY1R	P25929	5/20	0.61

▸	CCKBR	P32239	2/20	0.61

▸	GLP1R	P43220	2/20	0.61

▸	NPY4R	P50391	4/20	0.61

▸	NPY5R	Q15761	4/20	0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30721582	0.93	CALCR (0.76)	CALCRHCRTR1HCRTR2RAMP1RAMP2
SCHEMBL30721659	0.93	CALCR (0.76)	CALCRHCRTR1HCRTR2RAMP1RAMP2
SCHEMBL31182622	0.92	CALCR (0.72)	CALCRF2NPY2RNPY1RCCKBR
SCHEMBL31182791	0.92	CALCR (0.71)	CALCRHCRTR1HCRTR2RAMP3F2
SCHEMBL31182738	0.92	CALCR (0.67)	CALCRHCRTR1HCRTR2F2NPY2R
SCHEMBL29720295	0.92	CALCR (0.73)	CALCRHCRTR1HCRTR2RAMP1RAMP2
SCHEMBL29939723	0.92	CALCR (0.79)	CALCRHCRTR1HCRTR2NPY2RNPY1R
SCHEMBL31182875	0.92	NPY1R (0.69)	CALCRNPY2RNPY1RCCKBRGLP1R
SCHEMBL30658255	0.91	CALCR (0.77)	CALCRHCRTR1HCRTR2NPY2RNPY1R
SCHEMBL31148882	0.91	CALCR (0.78)	CALCRHCRTR1HCRTR2NPY2RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024119434-A1	SOLUBILIZATION-ASSISTING SHORT PEPTIDE TAG WITH ACIDIC SURFACE FOR IMPROVING EXPRESSION EFFICIENCY OF RECOMBINANT PROTEIN	宜明（济南）生物科技有限公司	2024-06-13	—	—	WO	disclosed