SCHEMBL29720295

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O)C(C)C)[C@@H](C)O

nearest known ligand 0.73

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	5/20	0.73

▸	RAMP1	O60894	1/20	0.73

▸	RAMP2	O60895	1/20	0.73

▸	RAMP3	O60896	1/20	0.73

▸	CALCRL	Q16602	1/20	0.73

▸	CRHR1	P34998	1/20	0.66

▸	CRHR2	Q13324	1/20	0.66

▸	GLP1R	P43220	5/20	0.65

▸	GCGR	P47871	3/20	0.65

▸	HCRTR1	O43613	1/20	0.65

▸	HCRTR2	O43614	1/20	0.65

▸	CCKBR	P32239	2/20	0.64

▸	NPY2R	P49146	6/20	0.64

▸	NPY4R	P50391	6/20	0.64

▸	NPY5R	Q15761	6/20	0.64

▸	NPY1R	P25929	4/20	0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2905167	0.98	CALCR (0.76)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL29519841	0.95	CALCR (0.71)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL30299016	0.95	CALCR (0.69)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL30362627	0.94	CALCR (0.70)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL29939723	0.93	CALCR (0.79)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL29706213	0.93	CALCR (0.74)	CALCRRAMP1RAMP2RAMP3CALCRL
SCHEMBL29593168	0.93	CALCR (0.79)	CALCRCRHR1CRHR2GLP1RHCRTR1
SCHEMBL29593747	0.93	CALCR (0.81)	CALCRCRHR1CRHR2GLP1RHCRTR1
SCHEMBL29592959	0.93	CALCR (0.79)	CALCRCRHR1CRHR2GLP1RHCRTR1
SCHEMBL30063048	0.92	CALCR (0.75)	CALCRRAMP1RAMP2RAMP3CALCRL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4736946-A2	AMYLIN ANALOGUES	Zealand Pharma A/S (DK)	2026-05-06	—	—	EP	disclosed
EP-4736945-A2	AMYLIN ANALOGUES	Zealand Pharma A/S (DK)	2026-05-06	—	—	EP	disclosed
US-12616737-B2	Liquid formulations of amylin analogues	ZEALAND PHARMA A/S (DK)	2026-05-05	—	—	US	disclosed
EP-4074729-B1	AMYLIN ANALOGUES	ZEALAND PHARMA AS (DK)	2026-04-15	—	—	EP	disclosed
CN-119923269-A	Combination therapy	西兰制药公司	2025-05-02	—	—	CN	disclosed
US-20250064895-A1	AMYLIN ANALOGUES	ZEALAND PHARMA A/S (DK)	2025-02-27	—	—	US	disclosed
US-20240335513-A1	LIQUID FORMULATIONS OF AMYLIN ANALOGUES	ZEALAND PHARMA A/S (DK)	2024-10-10	—	—	US	disclosed
WO-2024022465-A1	HUMAN AMYLIN POLYPEPTIDE DERIVATIVE AND USE THEREOF	杭州九源基因工程有限公司	2024-02-01	—	—	WO	disclosed
EP-4074729-A1	AMYLIN ANALOGUES	Zealand Pharma A/S (DK)	2022-10-19	—	—	EP	disclosed
US-11382956-B2	Amylin analogues	ZEALAND PHARMA A/S (DK)	2022-07-12	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-12616737-B2	Liquid formulations of amylin analogues	IAPP, IGFBP6, GLP1R	CALCR 265/4885RAMP1 1035/4885RAMP2 892/4885
US-20240335513-A1	LIQUID FORMULATIONS OF AMYLIN ANALOGUES	IAPP, GLP1R, GPR119	CALCR 1134/4885RAMP1 1974/4885RAMP2 2000/4885
US-20250064895-A1	AMYLIN ANALOGUES	IAPP, GLP1R, AMY2A	CALCR 532/4885RAMP1 1440/4885RAMP2 1466/4885
US-11382956-B2	Amylin analogues	IAPP, GLP1R, AMY2A	CALCR 532/4885RAMP1 1440/4885RAMP2 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.