Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.42 |
| ▸ | LCAT | P04180 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanide SCHEMBL27694903 | 0.95 | PANK3 (0.45) | CHRNA7MAPTUBE2TCHRM3PDE4A | |
| SCHEMBL12240393 | 0.95 | CHRNA7 (0.50) | CHRNA7MAPTUBE2TCHRM3PDE4A | |
| Hydrochloric Acid SCHEMBL27676371 | 0.89 | CHRNA7 (0.47) | CHRNA7MAPTUBE2TALDH1A1LMNA | |
| SCHEMBL2365777 | 0.84 | DDB1 (0.49) | ALDH1A1PANK3LCATSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL25318678 | 0.84 | CHRNA7 (0.45) | CHRNA7MAPTUBE2TALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL30476651 | 0.84 | CHRNA7 (0.45) | CHRNA7MAPTUBE2TALDH1A1LMNA | |
| SCHEMBL27848381 | 0.80 | PANK3 (0.43) | CHRNA7MAPTLMNAPANK3LCAT | |
| SCHEMBL27848379 | 0.80 | PANK3 (0.54) | ALDH1A1LMNAPANK3LCATACACB | |
| SCHEMBL29067295 | 0.80 | FASN (0.46) | CHRNA7MAPTUBE2TALDH1A1LMNA | |
| SCHEMBL30932097 | 0.80 | ACACB (0.43) | CHRNA7PANK3LCATACACBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-B | Phenylpyrrolidine compounds | 武汉人福创新药物研发中心有限公司 | 2024-06-14 | — | — | CN | disclosed |