Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 2/20 | 0.43 |
| ▸ | LCAT | P04180 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848379 | 0.82 | PANK3 (0.54) | PANK3LCATACACBKMT2AAKR1C3 | |
| SCHEMBL30932095 | 0.80 | CHRNA7 (0.48) | PANK3LCATACACBCHRNA7KMT2A | |
| SCHEMBL12240393 | 0.79 | CHRNA7 (0.50) | PANK3LCATCHRNA7KMT2AMAPT | |
| SCHEMBL28956353 | 0.76 | ME2 (0.55) | RETKMT2AMAPTAKR1C3NPC1 | |
| SCHEMBL29576869 | 0.76 | ME2 (0.55) | RETKMT2AMAPTAKR1C3NPC1 | |
| Cyanide SCHEMBL27694903 | 0.76 | PANK3 (0.45) | PANK3LCATACACBCHRNA7KMT2A | |
| SCHEMBL941651 | 0.76 | AKR1C3 (0.57) | PANK3RETKMT2AMEN1MAPT | |
| SCHEMBL2365777 | 0.76 | DDB1 (0.49) | PANK3LCATRETKMT2AKDM4E | |
| SCHEMBL18621601 | 0.76 | GRIN2D (0.51) | PANK3RETKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL27676371 | 0.75 | CHRNA7 (0.47) | PANK3LCATACACBCHRNA7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102239152-B | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP. (JP) | 2014-10-29 | — | — | CN | disclosed |
| CN-102239152-A | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2011-11-09 | — | — | CN | disclosed |