Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21378567 | 0.82 | HRH3 (0.51) | ACACBHRH3ALDH1A1GAAMAPT | |
| SCHEMBL21378570 | 0.82 | HRH3 (0.51) | ACACBHRH3ALDH1A1GAAMAPT | |
| SCHEMBL19177688 | 0.81 | HRH3 (0.49) | HRH3ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL14846679 | 0.81 | HRH3 (0.49) | HRH3ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL27761805 | 0.78 | HRH3 (0.56) | HRH3ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL27848477 | 0.77 | HRH3 (0.55) | HRH3ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL12699856 | 0.76 | HRH3 (0.61) | HRH3ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL30134231 | 0.76 | HRH3 (0.61) | HRH3ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL4547887 | 0.76 | HRH3 (0.65) | HRH3ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL10077424 | 0.75 | HRH3 (0.59) | HRH3ALDH1A1GAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253737-B3 | AUTOTAXIN INHIBITORY COMPOUNDS | CANCER RESEARCH TECH LTD (GB) | 2024-05-29 | — | — | EP | disclosed |