SCHEMBL30932689

SCHEMBL30932689

Oc1cc2c(cnn2C2CCCCO2)cc1C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 1/20 0.48
▸ RXRB P28702 1/20 0.48
▸ RXRG P48443 1/20 0.48
▸ CYP4F2 P78329 3/20 0.42
▸ CYP4A11 Q02928 3/20 0.42
▸ LMNA P02545 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ ATR Q13535 5/20 0.35
▸ PIK3CD O00329 2/20 0.32
▸ GRIN1 Q05586 1/20 0.31
▸ GRIN2B Q13224 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ CFTR P13569 1/20 0.31
▸ PDE8B O95263 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29015136 0.86 RXRA (0.46) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL30401675 0.86 RXRA (0.46) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL30998712 0.86 RXRA (0.46) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL29015135 0.85 RXRA (0.46) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL30401666 0.85 RXRA (0.46) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL20439390 0.81 RXRA (0.51) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL20437685 0.81 RXRA (0.51) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL20437571 0.81 RXRA (0.51) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL30380061 0.79 RXRA (0.51) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL28693246 0.79 RXRA (0.51) RXRARXRBRXRGCYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622643-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-10-01 — — EP disclosed
WO-2024112831-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2024-05-30 — — WO disclosed
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