Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.75 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.74 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.74 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | TNKS | O95271 | 6/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1772778 | 0.88 | HPGD (0.78) | HPGDKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL4650047 | 0.86 | HPGD (1.00) | HPGDKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL312255 | 0.85 | AKR1C3 (1.00) | HPGDKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL16670860 | 0.84 | HPGD (0.81) | HPGDKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL29370223 | 0.84 | HPGD (0.81) | HPGDKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL21704894 | 0.83 | HPGD (0.74) | HPGDKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL15676335 | 0.83 | HPGD (0.74) | HPGDKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL9080220 | 0.83 | AKR1C3 (0.72) | HPGDKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL21704890 | 0.82 | AKR1C3 (0.71) | HPGDKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL722615 | 0.81 | HPGD (1.00) | HPGDKDM4ECYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112731-A1 | FLAVONES, QUINOLINONES, QUINAZOLINONES, AND AURONES, AND USES IN CK2-MEDIATED DISEASES | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2024-05-30 | — | — | WO | disclosed |