Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.72 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.72 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 7/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312255 | 0.84 | AKR1C3 (1.00) | AKR1C3AKR1C2AKR1C1HPGDCYP3A4 | |
| SCHEMBL29370223 | 0.83 | HPGD (0.81) | AKR1C3AKR1C2AKR1C1HPGDCYP3A4 | |
| SCHEMBL16670860 | 0.83 | HPGD (0.81) | AKR1C3AKR1C2AKR1C1HPGDCYP3A4 | |
| SCHEMBL30933461 | 0.83 | HPGD (0.75) | AKR1C3AKR1C2AKR1C1HPGDCYP3A4 | |
| SCHEMBL4650047 | 0.81 | HPGD (1.00) | AKR1C3AKR1C2AKR1C1HPGDCYP3A4 | |
| SCHEMBL31061270 | 0.81 | HPGD (0.67) | AKR1C3AKR1C2AKR1C1HPGDCYP3A4 | |
| SCHEMBL530293 | 0.81 | HPGD (0.67) | AKR1C3AKR1C2AKR1C1HPGDCYP3A4 | |
| SCHEMBL21704890 | 0.81 | AKR1C3 (0.71) | AKR1C3AKR1C2AKR1C1HPGDCYP3A4 | |
| SCHEMBL7120599 | 0.80 | AKR1C3 (0.66) | AKR1C3AKR1C2AKR1C1HPGDCYP3A4 | |
| SCHEMBL722615 | 0.80 | HPGD (1.00) | AKR1C3AKR1C2AKR1C1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552551-A | COLORS FOR PHOSPHORESCENCE | FLORIDA STATE UNIVERSITY (US) | 1996-09-03 | — | — | US | disclosed |
| WO-1995003343-A1 | PROTON-TRANSFER, LOW SELF-ABSORBING CHROMOPHORES FOR USE IN SCINTILLATORS | FLORIDA STATE UNIVERSITY (US) | 1995-02-02 | — | — | WO | disclosed |