SCHEMBL30933543

SCHEMBL30933543

O=C(NCc1cccc2ccccc12)c1nn(CCO)c2c1CN(Cc1ccc(Cl)c(Cl)c1)CC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PEX14 O75381 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17554524 1.00 PEX14 (1.00) PEX14
SCHEMBL19294104 0.94 PEX14 (0.89) PEX14
SCHEMBL19294068 0.93 PEX14 (0.87) PEX14
SCHEMBL17576677 0.92 PEX14 (1.00) PEX14
SCHEMBL17576849 0.91 PEX14 (0.89) PEX14
SCHEMBL19294093 0.90 PEX14 (0.81) PEX14
SCHEMBL17576671 0.90 PEX14 (0.86) PEX14
SCHEMBL17576847 0.90 PEX14 (0.86) PEX14
SCHEMBL17576659 0.90 PEX14 (0.86) PEX14
SCHEMBL17576658 0.90 PEX14 (0.85) PEX14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3191484-B1 PYRAZOLOPYRIDINE DERIVATIVES AND THEIR USE IN THERAPY HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) 2024-06-12 EP disclosed