PEX14 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL17554524	1.00	20/20
SCHEMBL17576656	1.00	20/20
SCHEMBL17576677	1.00	20/20
SCHEMBL17576678	1.00	20/20
SCHEMBL17576846	1.00	20/20
SCHEMBL17576889	1.00	20/20
SCHEMBL17576890	1.00	20/20
SCHEMBL19294059	1.00	20/20
SCHEMBL19294060	1.00	20/20
SCHEMBL19294063	1.00	20/20
SCHEMBL19294064	1.00	20/20
SCHEMBL19294065	1.00	20/20
SCHEMBL19294066	1.00	20/20
SCHEMBL19294074	1.00	20/20
SCHEMBL19294075	1.00	20/20
SCHEMBL19294081	1.00	20/20
SCHEMBL19294090	1.00	20/20
SCHEMBL30933543	1.00	20/20
SCHEMBL19294116	0.91	20/20
SCHEMBL17576849	0.89	20/20

Clinical trials — most relevant to PEX14 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Compare the Impact of Xuezhikang and Atorvastatin on Glucose Metabolism in Dyslipidemia Patients With Prediabetes	PHASE4	COMPLETED
Pioglitazone Study of Triglyceride Changes in Subjects With Type 2 Diabetes After Conversion From Rosiglitazone.	PHASE4	COMPLETED
Betaine and Peroxisome Biogenesis Disorders	PHASE3	COMPLETED
TMC114-C209: A Study of Safety of TMC114 With Low Dose Ritonavir (RTV) and Other Antiretrovirals in Experienced HIV-1 Infected Patients With Limited or no Treatment Options	PHASE3	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension	PHASE1/PHASE2	RECRUITING
Cholic Acid for Hepatic Steatosis in Lipodystrophy	PHASE2	COMPLETED
A Supervised Nutritional Program in Pregnancies and NF-κB Expression in Placenta	PHASE1	COMPLETED
Vitreous Proteomics of Patients Suffering From Pseudoexfoliation Syndrome	nan	ACTIVE_NOT_RECRUITING
Plasma Levels of Matrix Metalloproteinases (MMPs) and Degree of DNA Fragmentation in Pseudoexfoliation (PEX) Glaucoma	nan	COMPLETED
Evaluation of a New Strategy for the Diagnosis of Peroxisomal Diseases	nan	COMPLETED
Evolution of Visual Impairment During Pseudoxanthoma Elasticum	nan	COMPLETED
Comparison of Phoenixin-14 Levels in Term Babies	nan	COMPLETED
The Effect of Laparoscopic Sleeve Gastrectomy on Blood Phoenixin-14 Levels	nan	COMPLETED
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease.	nan	UNKNOWN
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma	nan	RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Multi-Dimensional Genomic Dissection of Ring Chromosome 14 Syndrome	nan	ACTIVE_NOT_RECRUITING
Macrophages, GM-CSF and MARS Proteinosis	nan	COMPLETED
Longitudinal Prospective Natural History Study of Retinopathy in Zellweger Spectrum Disorder	nan	RECRUITING
Screening for Hepatitis Virus B Protein X (HBx) in Colitis-associated Cancer (CAC)	nan	NOT_YET_RECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis)	nan	COMPLETED
Gastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport Disorders	nan	UNKNOWN
Hydroxychloroquin (HCQ) in chILD of Genetic Defect	nan	COMPLETED
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions	nan	RECRUITING
Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse	nan	ACTIVE_NOT_RECRUITING
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism	nan	UNKNOWN
Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis.	nan	COMPLETED
Familial Partial Lipodystrophy Study	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a PEX14 binder may also engage these)

Protein	Name	Similarity
Q9R0A0	—	1.000	Q9R0A0 →
Q9Z2Z3	—	1.000	Q9Z2Z3 →
Q642G4	—	1.000	Q642G4 →
Q8K0V4	—	0.993	Q8K0V4 →
Q9HG09	—	0.992	Q9HG09 →
A0A0R4IZ84	—	0.992	A0A0R4IZ84 →
Q6NZJ6	—	0.992	Q6NZJ6 →
Q8BG95	—	0.992	Q8BG95 →
Q8IZ21	—	0.992	Q8IZ21 →
O60237	—	0.991	O60237 →
P78723	—	0.991	P78723 →
Q9DB00	—	0.991	Q9DB00 →
A5DLJ8	—	0.991	A5DLJ8 →
Q9D3S3	—	0.991	Q9D3S3 →
Q80Y56	—	0.991	Q80Y56 →
Q5XG48	—	0.991	Q5XG48 →
Q5RAK6	—	0.991	Q5RAK6 →
Q8IYB4	—	0.990	Q8IYB4 →
Q9D8L5	—	0.990	Q9D8L5 →
Q8BHX3	—	0.990	Q8BHX3 →
Q9ERE6	—	0.990	Q9ERE6 →
Q8WZL6	—	0.990	Q8WZL6 →
O35711	—	0.990	O35711 →
P84903	—	0.990	P84903 →
A7YDW0	—	0.990	A7YDW0 →
A5WV69	—	0.990	A5WV69 →
B5X601	—	0.989	B5X601 →
Q6AY97	—	0.989	Q6AY97 →
Q7SXL7	—	0.989	Q7SXL7 →
Q6DD45	—	0.989	Q6DD45 →