SCHEMBL30933699

SCHEMBL30933699

CCOc1ccc(Cl)cc1CNC1CCC(N)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPBWR1 P48145 1/20 0.49
MCHR1 Q99705 1/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2D6 P10635 2/20 0.49
POLB P06746 1/20 0.46
ATM Q13315 1/20 0.45
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HTR2C P28335 2/20 0.41
HTR2B P41595 2/20 0.41
MAPT P10636 2/20 0.41
HTR2A P28223 1/20 0.41
PKM P14618 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 1/20 0.39
OPRK1 P41145 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30933669 0.99 CYP1A2 (0.51) NPBWR1MCHR1CYP1A2CYP2D6POLB
SCHEMBL30933706 0.93 CYP1A2 (0.47) NPBWR1MCHR1CYP1A2CYP2D6POLB
Hydrochloric Acid SCHEMBL30933658 0.91 CYP1A2 (0.49) NPBWR1MCHR1CYP1A2CYP2D6POLB
SCHEMBL30933796 0.88 CYP1A2 (0.50) NPBWR1MCHR1CYP1A2CYP2D6POLB
Hydrochloric Acid SCHEMBL30933738 0.87 CYP1A2 (0.52) NPBWR1MCHR1CYP1A2CYP2D6POLB
SCHEMBL30933719 0.86 HTR2C (0.45) NPBWR1MCHR1CYP1A2CYP2D6KMT2A
Hydrochloric Acid SCHEMBL30933663 0.85 HTR2C (0.46) NPBWR1MCHR1CYP1A2CYP2D6KMT2A
SCHEMBL30933688 0.84 POLB (0.50) NPBWR1MCHR1CYP1A2CYP2D6POLB
SCHEMBL30933787 0.82 ALDH1A1 (0.48) NPBWR1MCHR1CYP1A2CYP2D6POLB
SCHEMBL30933775 0.82 CYP1A2 (0.51) NPBWR1MCHR1CYP1A2CYP2D6POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105007-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2024-05-23 WO disclosed