Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933789 | 1.00 | CYP1A2 (0.54) | CYP1A2CYP2D6ATMPOLBLMNA | |
| Hydrochloric Acid SCHEMBL30933732 | 0.99 | CYP1A2 (0.56) | CYP1A2CYP2D6ATMPOLBLMNA | |
| Hydrochloric Acid SCHEMBL30933678 | 0.99 | CYP1A2 (0.56) | CYP1A2CYP2D6ATMPOLBLMNA | |
| SCHEMBL30933773 | 0.93 | CYP2D6 (0.56) | CYP1A2CYP2D6ATMPOLBLMNA | |
| Hydrochloric Acid SCHEMBL30933803 | 0.92 | CYP1A2 (0.58) | CYP1A2CYP2D6ATMPOLBLMNA | |
| SCHEMBL30933712 | 0.91 | MAPT (0.50) | CYP1A2CYP2D6ATMPRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL30933786 | 0.90 | MAPT (0.49) | CYP1A2CYP2D6ATMLMNAPRMT5 | |
| Hydrochloric Acid SCHEMBL30933661 | 0.87 | SLC6A4 (0.44) | CYP1A2CYP2D6PRMT5WDR77SLC6A2 | |
| SCHEMBL30933772 | 0.84 | MAPT (0.52) | CYP1A2CYP2D6ATMPRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL30933667 | 0.82 | PRMT5 (0.47) | CYP1A2CYP2D6ATMLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |